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Whole genome sequencing
Identify genetic mutations by profiling hundreds of single cells in parallel and discover the underlying cause of cellular malfunctioning.
- Detect SNVs within single cells
- Low-cost WGS
- Range of coverage for different applications
Karyotyping
Identify copy number variations (CNVs) within a chromosome or at the whole chromosome level (aneuploidy) in the genome by profiling hundreds of single cells in parallel and discover the underlying cause of cellular malfunctioning.
- Discover CNVs as small as 2 Mbs per cell
- Assess the aneuploidy of your sample
- Low-cost karyotyping
Chromatin profiling
Look at the specific epigenetic factors influencing DNA-protein binding to regulate gene expression.
- Low number of input cells required compared to ChIP-seq
- Readily available for key driver histone modifications
- Including in-house cell sorting
Single-cell data analysis
Need help with your data analysis, statistics or figure design? Let Single-Cell Core link you to a highly trained bioinformatician.
About Single-cell data analysisBulk DNA sequencing
Bulk DNA sequencing is the standard tool to generate (epi)genomic data at cell population level.
- More powerful and cost-effective compared to scDNA-seq
- Low number of 100 input cells required
- Can be applied to all our available techiques
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test@test.nl
06345345
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